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Low Copy Number (LCN) is a DNA profiling technique developed by the Forensic Science Service (FSS) which has been in use since 1999. In the United Kingdom use of the technique was suspended between 21 December 2007 and 14 January 2008 while the Crown Prosecution Service conducted a review into its use - this suspension has now been lifted.〔(CPS Press Release : Review of the use of Low Copy Number DNA analysis in current cases: CPS statement )〕 LCN is an extension of Second Generation Multiplex Plus (SGM Plus) profiling technique. It is a more sensitive technique because it involves a greater amount of copying via polymerase chain reaction (PCR) from a smaller amount of starting material, meaning that a profile can be obtained from only a few cells, which may be as small as a millionth the size of a grain of salt, and amount to a just few cells of skin or sweat left from a fingerprint.〔(DNA test halted after Omagh case ), BBC〕 == Advantages == LCN evidence has allowed convictions to be made in several cold cases. For example, Mark Henson was convicted of rape in 2005, 10 years after the crime was committed, from re-analysis of a microscope slide.〔(THE FORENSIC SCIENCE SERVICE, Fact sheet (6), Cold cases ), (PDF)〕 In 1981, evidence was deliberately kept after the rape and murder of 14-year-old Marion Crofts. In 1999, a DNA profile was obtained from this using LCN. This was continually checked against the UK National DNA Database for the next two years, until a match was eventually found for Tony Jasinskyj after he was arrested for another crime. He was eventually given a life sentence in 2002.〔(Marion Crofts ), FSS〕 So far the technique is only used in several countries:the UK, the Netherlands and New Zealand.(Citation: NATURE|Vol 464|18 March 2010) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Low copy number」の詳細全文を読む スポンサード リンク
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